Introducing
Spacing the Prostate from the Rectal Wall
Reduced Rectal and Urinary Toxicity
Now Privately Reimbursed

For Doctors

SpaceOAR has been referred to as ‘The Game Changer’ by many of Australia’s leading Radiation Oncologists and Urologists. 
The intent of SpaceOAR is to create a physical space between the prostate and the anterior rectal wall intended to prevent the rectum from exposure to radiation. SpaceOAR is a hydrogel made of polyethylene glycol that is fully synthetic, water soluble, non-toxic and non-immunogenic. As a hydrogel SpaceOAR solidifies once injected, creating a space of approximately 1cm for a three month period. This allows for a normal EBRT program to run its course at the end of which SpaceOAR will liquefy and be absorbed and excreted renally by 6 months. 
The injection is via the transperineal route similar to that of an LDR or transperineal fiducial marker procedure. TRUS guidance is needed to visual the procedure which takes approximately 5-10 minutes. SpaceOAR can be used in conjunction with any RT modality including EBRT, LDR, HDR, IMRT, IGRT, Proton, SRS etc.
The latest multi-institutional phase II trial data has show “… no patients had early late GI or GU toxicity ≥ Grade 2.”1 Current studies in Australia have had similar reductions in toxicity and many sites have adapted SpaceOAR as part of general practice for all RT modalities. 
SpaceOAR is now fully reimbursed via the Prosthesis list for insured patients. Though available for public patients many public hospitals do not offer SpaceOAR currently. Radiation Oncology Victoria and parent company Genesis Cancer Care are currently running a campaign whereby public patients who are eligible for SpaceOAR can receive the treatment as part of their overall radiotherapy at no charge where suitable.  For contact information please view their page at:
http://www.radoncvic.com.au/spaceoar
See the below video for insertion technique.

Uhl M et al. Low rectal toxicity after dose escalated IMRT treatment of prostate cancer using an absorbable hydrogel for increasing and maintaining space between the rectum and prostate: Results of a multi-institutional phase II trial. Radiother Oncol (2013), http://dx.doi.org/10.1016/j.radonc.2012.11.009

Are you looking to advance your cancer service with people experienced with SpaceOAR? Speak with Precision Cancer Care –
www.precisioncancercare.com.au

 

For Patients

SpaceOAR has been referred to as ‘The Game Changer’ by many of Australia’s leading Radiation Oncologists and Urologists. 
With the advances of radiation therapy technology more patients are contemplating  radiation therapy instead of traditional surgery for their prostate cancer treatment. In some cases this can be a personal choice, avoidance of surgery or recommended by either Urologist or Radiation Oncologist. 
Historically the greatest side effects of radiation therapy for prostate cancer have been the exposure of the rectal wall to radiation dose meant for the prostate. This is because for the majority of men the rectal wall sits directly beneath the prostate separated by a thin layer of fascia (very thin muscle-like layer) and fat. 
All types of radiation therapy treatments from EBRT (External Beam Radiotherapy: Beams shot from outside of the body to the tumor), HDR (High Dose Rate: Needles stuck into the prostate that emit radiation and are withdrawn after treatment) or LDR (Low Dose Rate: Minuscule titanium seeds that are infused with radiation that stay in the prostate.)  emit radiation in varying concentrated fields – strongest in the center and weaker in the outer fields.
If you imagine a torch that has varying circular fields of intensity, the most intense light will be in the center field of the torches light, becoming gradually weaker as it extends out. It is the strongest center field of this ‘light’ that radiation therapy is aiming to hit your prostate with. Unfortunately as your rectal wall can be pressed hard against your prostate these stronger, inner fields of the radiation can sometimes hit your rectal wall causing damage and consequential side effects.
SpaceOAR is a hydrogel, meaning that it will eventually become a liquid and be reabsorbed into your body, which aims to create a space between your prostate and your rectal wall. By physically pushing your rectal wall away from your prostate SpaceOAR aims to push your rectal wall into the outer, weaker fields which have a much weaker ‘light’ intensity. By doing this studies have shown the chances of having toxicity related side effects such as chronic diarrhea, discharge, incontinence and more are greatly reduced.

More information and study data can be seen at: 

www.augmenix.com 
or contact Product Manager Xavier Lawrence
xavier.lawrence@mdsanz.com

 

 

 

 

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